Scientific Program


  • Wednesday, September 20, 2017 – Afternoon

  • 16.00–17.00

  • Registration

  • 17.00–17.30

  • Opening ceremony

  • OPENING LECTUREChair: V. Andrisano

  • 17.30–18.30

    OL

    Abs

  • Vincenzo Balzani

    University of Bologna, Italy

    Chemistry and creativity: From photochemistry to molecular machines

  • 18.45

  • Welcome buffet

  • Thursday, September 21, 2017 – Morning

  • PLENARY LECTUREChair: G. Massolini

  • 9.00–9.45

    PL01

    Abs

  • Kelly Zhang

    Genentech, USA

    Challenges and recent advances in pharmaceutical analysis: An industry perspective

  • SESSION 1 – Drug analysis: Large molecules – Chair: K. Zhang, I.A. Kaltashov

  • 9.45–10.05

    OC01

  • Laura Tigli

    Chiesi Farmaceutici, Italy

    Strategies for biopharmaceutical characterization: Two real case studies

  • 10.05–10.25

    OC02

  • Regina Römling

    Tosoh Bioscience, Germany

    UHPLC analysis in biopharmaceutical R&D and production

  • 10.25–10.45

    OC03

  • Julien Camperi

    CNRS - ESPCI Paris, France

    New nanoLC-HRMS and CE-MS methods for the characterization of the intact glycoforms of the human chorionic gonadotropin protein

  • 10.45–11.10

  • Coffee break

  • SESSION 2 – Drug analysis: Counterfeiting, doping and forensic – Chair: S. Rudaz, K. Wanner

  • 11.10–11.40

    KN01

    Abs

  • Simona Francese

    Sheffield Hallam University, UK

    Criminal profiling through MALDI MS based technologies

  • 11.40–12.00

    OC04

  • Maria Kristina Parr

    Freie Universität Berlin, Germany

    Old friends, new relatives – the science behind recent revelation of doping abuse at Beijing and London Olympics

  • 12.10–12.20

    OC05

  • Bernhard Wüst

    Agilent Technologies, Germany

    Identification of drugs and drug metabolites in forensic and doping control applications using high resolution accurate mass QTOF instrumentation

  • 12.20–13.05

  • Lunch

  • 13.05–14.05

  • Poster session

  • Thursday, September 21, 2017 – Afternoon

  • SESSION 3 – Natural products – Chair: Y.H. Choi, E. De Lorenzi

  • 14.05–14.35

    KN02

    Abs

  • Young Hae Choi

    Leiden University, The Netherlands

    Mixture analysis by NMR: from an identification tool to quantitative analysis and a profiling technique

  • 14.35–14.55

    OC06

  • Gabriella Roda

    University of Milan, Italy

    Ripe vs Raw Pu'er tea: LC-MS, antioxidant and anti-enzyme profiling of aqueous extracts

  • 14.55–15.15

    OC07

  • Markus Ganzera

    University of Innsbruck, Austria

    Analysis of natural products by supercritical fluid chromatography

  • 15.15–15.35

    OC08

  • Federica Pellati

    University of Modena and Reggio Emilia, Italy

    Development of a new extraction technique and HPLC method for the analysis of non-psychoactive cannabinoids in fibre-type Cannabis sativa L. (hemp)

  • 15.35–16.00

  • Coffee break

  • SESSION 4 – Young researchers (1) – Chair: G.W. Somsen, R. Sardella

  • 16.00–16.30

    KN03

    Abs

  • Govert W. Somsen

    Vrije Universiteit Amsterdam, The Netherlands

    Microheterogeneity assessment of intact pharmaceutical proteins by LC-MS and CE-MS

  • 16.30–16.43

    FC01

  • Nicolas Eskenazi

    CNRS - ESPCI Paris, France

    Human chorionic gonadotropin glycoproteoforms characterization using hydrophilic affinity enrichment and mass spectrometry approaches

  • 16.43–16.56

    FC02

  • Giovanna Baron

    University of Milan, Italy

    Profiling Vaccinium Macrocarpon components and metabolites in human urine

  • 16.56–17.09

    FC03

  • Edoardo Fabini

    University of Bologna, Italy

    Exploring the drugable space of epigenetic target SMYD3: A bioanalytical approach

  • Friday, September 22, 2017 – Morning

  • PLENARY LECTUREChair: M. Carini

  • 9.00–9.45

    PL02

    Abs

  • Jean-Luc Veuthey

    University of Geneva, University of Lausanne, Switzerland

    SFC and SFC-MS in drug analysis: Dream or reality?

  • SESSION 5 – Drug analysis: Small molecules – Chair: J.L. Veuthey, V. Pichon

  • 9.45–10.05

    OC09

  • Erwin Adams

    KU Leuven, Belgium

    Determination of residual solvents in drug loaded mesoporous silica using thermal desorption–gas chromatography

  • 10.05–10.25

    OC10

  • Caterina Temporini

    University of Pavia, Italy

    Application of HPLC-MS/MS to related impurities in fermentation products

  • 10.25–10.45

    OC11

  • Emidio Camaioni

    University of Perugia, Italy

    Prediction and experimental determination of the pKa of small organic compounds

  • 10.45–11.10

  • Coffee break

  • SESSION 6 – Metabolomics and lipidomics – Chair: C. Barbas, G. Aldini

  • 11.10–11.40

    KN04

    Abs

  • Coral Barbas

    Universidad San Pablo CEU, Spain

    Metabolomics uncovers postmortem changes in brain important in preclinical drug development

  • 11.40–12.00

    OC12

  • Serge Rudaz

    University of Geneva, Switzerland

    Unravelling the effects of multiple experimental factors in metabolomic studies

  • 12.00–12.20

    OC13

  • Marica Orioli

    University of Milan, Italy

    Profiling skin lipid composition by shotgun lipidomics approaches

  • 12.20–13.05

  • Lunch

  • 13.05–14.05

  • Poster session

  • Friday, September 22, 2017 – Afternoon

  • SESSION 7 – Sample preparation and method validation – Chair: S. Pedersen-Bjergaard, G. Grosa

  • 14.05–14.35

    KN05

    Abs

  • Stig Pedersen-Bjergaard

    University of Oslo, Norway

    Recent trends in drug analysis using liquid-phase microextraction

  • 14.35–14.55

    OC14

  • Valérie Pichon

    CNRS - ESPCI Paris, France

    Miniaturization of selective extraction devices for their on-line coupling with capillary chromatography

  • 14.55–15.15

    OC15

  • Jessica Fiori

    University of Bologna, Italy

    Simultaneous SPME-GC/MS analysis of short chain fatty acids, trimethylamine and trimethylamine N-oxide for gut microbiota metabolic profile

  • 15.15–15.40

  • Coffee break

  • SESSION 8 – Young researchers (2) – Chair: M. Fillet, E. Adams

  • 15.40–16.10

    KN06

    Abs

  • Marianne Fillet

    University of Liège, Belgium

    Blood microsampling for itraconazole pharmacokinetic study on individual rodent in the context of drug formulation optimization

  • 16.10–16.23

    FC04

  • Cinzia Citti

    Università del Salento, Italy

    Untargeted rat brain metabolomics after oral administration of a single high dose of cannabidiol

  • 16.23–16.36

    FC05

  • Michele dei Cas

    University of Milan, Italy

    Screening of new psychoactive substances (NPS) by gas-chromatography/time of flight mass spectrometry (GC/MS-TOF)

  • 16.36–16.49

    FC06

  • Federica Ianni

    University of Perugia, Italy

    Hydrophilic interaction liquid chromatography with diol-type stationary phases: case studies

  • 16.49–17.02

    FC07

  • Johan Cailletaud

    University of Liège, Belgium

    Towards a covering aerospray method for quantitative analyses of pharmaceutical tablets using surface-enhanced Raman chemical imaging (SERS-CI)

  • 17.02–17.15

    FC08

  • Laura Fumagalli

    University of Milan, Italy

    Unexpected reactivity of the antiseptic domiphen bromide

  • 17.15–17.28

    FC09

  • Ettore Gilardoni

    University of Milan, Italy

    Probing the reactivity of carnosine with 4-hydroxynonenal and the stability of the corresponding Michael adduct in biological matrices by liquid chromatography–mass spectrometry techniques

  • 20.30

  • Social dinner

  • Saturday, September 23, 2017 – Morning

  • SESSION 9 – Analytical approaches for drug target interaction – Chair: M. Przybylski, I.W. Wainer

  • 9.00–9.30

    KN07

    Abs

  • Michael Przybylski

    Steinbeis Centre for Biopolymer Analysis & Biomedical Mass Spectrometry, Germany

    New perspectives for protein immunotherapy and vaccine development through antibody epitope identification using affinity-mass spectrometry

  • 9.30–9.50

    OC16

  • Klaus Wanner

    Ludwig-Maximilians-Universität München, Germany

    Simultaneous multiple MS binding assays addressing D1 and D2 dopamine receptors

  • 9.50–10.10

    OC17

  • Alessandra Altomare

    University of Milan, Italy

    Set-up of an innovative analytical strategy for the identification and characterization of molecular interactors of the receptor for advanced glycation end products (RAGE)

  • 10.10–10.30

    OC18

  • Darius Widera

    University of Reading, UK

    A novel cell-based screening system for investigation of neuroinflammation

  • 10.30–10.50

    OC19

  • Francesco Tamagnini

    University of Exeter, UK

    Use of single-cell electrophysiology to characterize Alzheimer’s disease-associated altered neuronal excitability

  • 10.50–11.15

  • Coffee break

  • 11.15–11.45

    KN08

    Abs

  • Igor A. Kaltashov

    University of Massachussetts Amherst, USA

    Analysis of highly heterogeneous macromolecular medicines using a novel top-down platform based on native LC/MS/MS

  • CLOSING LECTUREChair: C. Bertucci

  • 11.45–12.35

    CL

    Abs

  • Irving W. Wainer

    Mitchell Woods Pharmaceuticals, USA

    The adventures of a bioanalytical chemist in the never-never land of antidepressants: using metabolomics to find a solution to the "ketamine paradigm"

  • 12.35–13.00

  • Closing remarks